Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable b-cell defects, and the presence of recurrent bacterial infections.

Common variable immunodeficiency (CVID) is an inborn immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM, and IgA. Symptoms generally include high susceptibility to pathogens, chronic lung disease, as well as inflammation and infection of the gastrointestinal tract. CVID affects males and females equally...